Flu mutates quicker than thought Flu viruses can swap many genes rapidly to make new resistant strains, US researchers have found. Scientists previously believed that gene swapping progressed gradually from season to season. The findings in PLOS Biology suggest strains could vary widely each season, making it potentially harder to treat. They also increase concerns about bird flu mutating to spread readily between humans. Dr David Lipman and colleagues looked at strains of influenza A that had circulated between 1999 and 2004 in New York. These strains had given rise to the so-called Fujian strain H3N2 that caused a troublesome outbreak in the 2003-2004 flu season because the vaccine made that winter was a poor match for the virus. Dr Lipman's team found wide variations in the 156 strains that they analysed. Some of the strains had at least four gene swaps that had occurred in a short time period. "The genetic diversity of influenza A virus is therefore not as restricted as previously suggested," said the researchers. Scientists have been particularly worried recently about avian flu mutating and acquiring the ability to spread from human to human. If it does, it could kill millions worldwide. Professor John Oxford, a virologist at Queen Mary's School of Medicine, said: "Their work shows that, overall, the virus is a lot more busy swapping genes than we ever thought it was. "The situation could be similar in the bird flus as well." http://news.bbc.co.uk/1/hi/health/4717183.stm ----------------------------------------------- FURTHER REFERENCES GO - "search perceptions" - in SEARCH-ENGINE file-ID www.perceptions.couk.com/genes22.txt